The 4th Takao Forum of Oral and Maxillofacial Surgery and Regenerative Medicine WFU

2026年9月28日月曜日

Firdaus HARIRI

Firdaus HARIRI





Dr. Firdaus Hariri is a professor and senior consultant in oral maxillofacial surgery at University of Malaya Medical Centre (UMMC), Department of Oral and Maxillofacial Clinical Sciences, Faculty of Dentistry Universiti Malaya and University of Malaya Specialist Centre. He obtained both his dental and medical degrees from Universiti Malaya (UM) and completed his oral and maxillofacial surgery training with distinction at Queen Mary Hospital and Prince Philip Dental Hospital, The University of Hong Kong (HKU). He later had his craniofacial attachments at various established craniofacial centres abroad and subsequently obtained his Master of Science in Molecular Medicine from International Medical University (IMU). In addition to routine maxillofacial surgical practices such as orthognathic surgery, trauma and oral implantology, his subspecialty and research interests are focused on pediatric craniofacial and reconstructive surgery, tissue engineering in particular distraction osteogenesis technique, bone regeneration for oral rehabilitation and the field of neurotrauma. He has more than 70 academic publications and is actively involved in national and international scientific conferences, consultations and organizations. He is one of the founding members and currently the lead coordinator for the multidisciplinary craniofacial clinic in UMMC, the team leader for Oro-Craniomaxillofacial Research and Surgical (OCReS) group at the Faculty of Dentistry UM, subspecialty coordinator for the Fellowship in Advanced Craniomaxillofacial Surgery (FACS) UM, and the chairman of National Dental Specialty Education Committee (DentSEdC) for oral and maxillofacial surgery.

He currently serves as the Dean of Faculty of Dentistry UM and Strasbourg Osteosynthesis Group Southeast Asia (SEA) Chairman.



Keiichiro MIURA

Keiichiro MIURA






2007: DDS, School of Dentistry, Tohoku University, Sendai, Japan

2012: PhD, Tohoku University Graduate School of Dentistry, Sendai, Japan

2012: Assistant Professor, Department of Regenerative Oral Surgery, Nagasaki                         University Graduate School of Biomedical Sciences, Nagasaki, Japan

2020: Assistant Professor, Division of Oral and Maxillofacial Surgery, Department of Oral Medicine and Surgery, Tohoku University Graduate School of Dentistry, Sendai, Japan

2022: Lecturer, Department of Oral Surgery, Nagasaki University Hospital, Nagasaki, Japan

2023: Clinical Fellowship, Department of Oral and Maxillofacial Surgery, Kaohsiung Medical University, Kaohsiung, Taiwan

2025 - Present: Lecturer, Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan


  • Speciality/Professional Certifications

2016: Board-Certified Specialist, Japanese Society of Oral and Maxillofacial          Surgeons

2018: Board-Certified Clinical Oncologist, Japanese Board of Cancer Therapy

2018: Fellow of the International Board for the Certification of Specialists in Oral and Maxillofacial Surgery (FIBCSOMS)

2024: Board-Certified Instructor, Japanese Society of Oral and Maxillofacial Surgeons


Publications

  1. Miura KI, Sakamoto Y, Yoshimine H, Iwamoto H, Yamada T, Umeda M, Yamada SI. Clinical considerations for oral appliance use in obstructive sleep apnea patients with dental implants: a scoping review. Sleep Breath. 2026 Aug 29;30(5):246. doi: 10.1007/s11325-026-03793-x. PMID: 42667470.


  1. Ohnuma M, Umeda M, Omori K, Miura KI, Sakamoto Y, Otsuru M, Yamada T. Potential relationship among CT and MRI imaging, histological findings, and treatment outcomes in patients with medication-related osteonecrosis of the jaw undergoing segmental mandibulectomy- A retrospectives study. J Dent Sci. 2025 Jul;20(3):1523-1531. doi: 10.1016/j.jds.2024.12.020. Epub 2024 Dec 28. PMID: 40654480; PMCID: PMC12254790.


  1. Fukushima H, Naruse T, Furukawa K, Omori K, Miyoshi T, Miura KI, Otsuru M, Umeda M. Extranodal Extension and Epithelial Cell Adhesion Molecule Over-expression in Oral Squamous Cell Carcinoma. Anticancer Res. 2023 Nov;43(11):5155-5166. doi: 10.21873/anticanres.16716. PMID: 37909986.


  1. Imakiire A, Soutome S, Nakamura Y, Nakamatsu M, Miura K, Sakamoto Y, Umeda M. A novel method for determining viable bacteria from a mixture of dead and viable bacteria: Delayed real-time PCR (DR-PCR) method. J Microbiol Methods. 2023 Nov;214:106844. doi: 10.1016/j.mimet.2023.106844. Epub 2023 Oct 17. PMID: 37858897.


  1. Niimi T, Soutome S, Imakiire A, Imura H, Hara M, Miura KI, Otsuru M, Yamada T, Umeda M, Natsume N. Relationship Between Postoperative Feeding Status and Salivary Bacterial Load Following Oral Surgical Procedures. Cureus. 2025 Jul 27;17(7):e88862. doi: 10.7759/cureus.88862. PMID: 40873818; PMCID: PMC12380502.


  1. Miura K, Takaoka H, Ota M, Irie R, Ota J, Noguchi Y, Nishikawa Y, Yoshida K, Suzuki K, Aoki S, Yashima S, Kinoshita M, Suzuki-Eguchi N, Sasaki H, Kobayashi Y. Utility of Computed Tomography for the Initial Detection and Follow-up of Silent Coincidence of IgG4-Related Pericarditis, Periaortitis, and Coronary Arteritis. Circ Rep. 2024 Jan 16;6(2):28-29. doi: 10.1253/circrep.CR-23-0086. PMID: 38344389; PMCID: PMC10853631.


  1. Miyoshi T, Otsuru M, Morishita K, Omori K, Miura KI, Hayashida S, Rokutanda S, Matsushita Y, Umeda M, Yamada T. Differences Between Medication-Related Osteonecrosis of the Jaw Caused by Bisphosphonates and Denosumab: Histological, Molecular Biological, and Clinical Studies. Cureus. 2024 Jun 21;16(6):e62855. doi: 10.7759/cureus.62855. Erratum in: Cureus. 2025 Feb 4;17(2):c210. doi: 10.7759/cureus.c210. PMID: 39036251; PMCID: PMC11260442.


  1. Nakamura N, Otsuru M, Miyoshi T, Suyama K, Omori K, Morishita K, Soutome S, Rokutanda S, Miura KI, Umeda M. Risk factors for the development of medication-related osteonecrosis of the jaw and effects of tooth extraction with local infection. J Dent Sci. 2024 Jul;19(3):1770-1782. doi: 10.1016/j.jds.2023.10.006. Epub 2023 Oct 13. PMID: 39035297; PMCID: PMC11259623.


  1. Imakiire A, Soutome S, Miura KI, Ito N, Higaki M, Obayashi F, Koizumi K, Yanamoto S, Yamada T, Umeda M. Effect of Oral Application of Povidone-Iodine on the Amount of Viable Bacteria Entering the Lower Respiratory Tract in Intubated Patients With Oral Cancer: A Preliminary Study. Cureus. 2024 Oct 23;16(10):e72240. doi: 10.7759/cureus.72240. PMID: 39583361; PMCID: PMC11584329.


  1. Kawai T, Kamakura S, Matsui K, Fukuda M, Takano H, Iino M, Ishikawa S, Kawana H, Soma T, Imamura E, Kizu H, Michibata A, Asahina I, Miura K, Nakamura N, Kibe T, Suzuki O, Takahashi T. Clinical study of octacalcium phosphate and collagen composite in oral and maxillofacial surgery. J Tissue Eng. 2020 Jan 23;11:2041731419896449. doi: 10.1177/2041731419896449. PMID: 32030119; PMCID:PMC6978823.


  1. Suyama K, Otsuru M, Nakamura N, Morishita K, Miyoshi T, Omori K, Miura KI, Soutome S, Hayashida S, Rokutanda S, Umeda M. Bone resection methods in medication-related osteonecrosis of the jaw in the mandible: An investigation of 206 patients undergoing surgical treatment. J Dent Sci. 2024 Jul;19(3):1758-1769. doi: 10.1016/j.jds.2023.10.007. Epub 2023 Oct 13. PMID: 39035329; PMCID: PMC11259631.


  1. Miura KI, Sasaki M, Ohba S, Noda S, Sumi M, Kamakura S, Takahashi T, Asahina I. Long-term clinical and radiographic evaluation after maxillary sinus floor augmentation with octacalcium phosphate-collagen composite: A retrospective case series study. J Tissue Eng Regen Med. 2022 Jul;16(7):621-633. doi: 10.1002/term.3301. Epub 2022 Mar 28. PMID: 35347853.


  1. Kono Y, Miura K, Kasai H, Ito S, Asahina M, Tanabe M, Nomura Y, Nakaguchi T. Breath Measurement Method for Synchronized Reproduction of Biological Tones in an Augmented Reality Auscultation Training System. Sensors (Basel). 2024 Mar 1;24(5):1626. doi: 10.3390/s24051626. PMID: 38475162; PMCID: PMC10934352.


  1. Ohnuma M, Otsuru M, Omori K, Morishita K, Hayashida S, Soutome S, Miura KI, Umeda M, Yamada T. A retrospective study on odontogenic and non-odontogenic medication-related osteonecrosis of the jaw: Potential differences in clinical features and treatment outcomes. J Dent Sci. 2025 Apr;20(2):1035-1042. doi: 10.1016/j.jds.2024.11.021. Epub 2024 Dec 3. PMID: 40224065; PMCID: PMC11993003.


  1. Miura KI, Otsuru M, Fukushima H, Omori K, Naruse T, Umeda M, Yamada T. Clinical Study on Postoperative Treatment for Patients at High Risk of Oral Squamous Cell Carcinoma Recurrence. Cureus. 2025 Feb 2;17(2):e78395. doi: 10.7759/cureus.78395. PMID: 40046372; PMCID: PMC11880635.


  1. Miura KI, Sumita Y, Kajii F, Tanaka H, Kamakura S, Asahina I. First clinical application of octacalcium phosphate collagen composite on bone regeneration in maxillary sinus floor augmentation: A prospective, single-arm, open-label clinical trial. J Biomed Mater Res B Appl Biomater. 2020 Jan;108(1):243-252. doi: 10.1002/jbm.b.34384. Epub 2019 Apr 13. PMID: 30980703.


  1. Miura KI, Sumi M, Umeda M, Umeda M, Yamada T. A Case of Diffuse Sclerosing Osteomyelitis (DSO) Initially Diagnosed as Bacterial Mandibular Osteomyelitis and Successfully Treated With Bisphosphonate Administration (Ibandronate). Cureus. 2024 Dec 22;16(12):e76210. doi: 10.7759/cureus.76210. PMID: 39840181; PMCID: PMC11750254.


  1. Miura KI, Yoshida M, Rokutanda S, Koga T, Umeda M. Swallowing Functions after Sagittal Split Ramus Osteotomy with Loose Fixation for Mandibular Prognathism: A Retrospective Case Series Research. Int J Environ Res Public Health. 2023 Jan 20;20(3):1926. doi: 10.3390/ijerph20031926. PMID: 36767291; PMCID: PMC9916000.


  1. Takahara M, Kitahara H, Nishi T, Miura K, Miyayama T, Sugimoto K, Nakayama T, Fujimoto Y, Kobayashi Y. Very early tissue coverage after drug-eluting stent implantation: an optical coherence tomography study. Int J Cardiovasc Imaging. 2017 Jan;33(1):25-30. doi: 10.1007/s10554-016-0972-3. Epub 2016 Sep 6. PMID: 27601229.


  1. makiire A, Soutome S, Miura K, Ito N, Higaki M, Obayashi F, Koizumi K, Yanamoto S, Yamada T, Umeda M. Potential effect of topical antibiotics administration in the oral cavity on the reduced number of bacteria entering the lower respiratory tract after oral cancer surgery. J Dent Sci. 2025 Jan;20(1):319-324. doi: 10.1016/j.jds.2024.06.021. Epub 2024 Jul 15. PMID: 39873031; PMCID: PMC11762615.


  1. Wu CC, Kao YH, Kim YD, Ting CC, Chen H, Wu FC, Miura K, Ogasawara T, Hoshi K, Lo WL, Chen YC, Jeng JH, Ko EC. Impact of red-lime and white-lime betel quid on oral cell lines: Cytotoxicity and effects on fibronectin and type I collagen expression. J Dent Sci. 2025 Apr;20(2):819-829. doi: 10.1016/j.jds.2024.09.011. Epub 2024 Oct 8. PMID: 40224095; PMCID: PMC11993079.


  1. Miura KI, Otsuru M, Omori K, Naruse T, Umeda M, Yamada T. Prognostic Factors in Squamous Cell Carcinoma of the Maxillary Gingiva and Hard Palate: A Retrospective Analysis From a Single Institution. Cureus. 2025 Feb 4;17(2):e78487. doi: 10.7759/cureus.78487. PMID: 40051924; PMCID: PMC11884383.


  1. Miyoshi T, Otsuru M, Morishita K, Omori K, Miura KI, Hayashida S, Rokutanda S, Matsushita Y, Umeda M, Yamada T. Correction: Differences Between Medication- Related Osteonecrosis of the Jaw Caused by Bisphosphonates and Denosumab: Histological, Molecular Biological, and Clinical Studies. Cureus. 2025 Feb 4;17(2):c210. doi: 10.7759/cureus.c210. Erratum for: Cureus. 2024 Jun 21;16(6):e62855. doi: 10.7759/cureus.62855. PMID: 39911288; PMCID: PMC11795217.


  1. Shido R, Sumita Y, Hara M, Iwatake M, Narahara S, Umebayashi M, Miura KI, Kodama Y, Asahina I. Gene-activated matrix harboring a miR20a-expressing plasmid promotes rat cranial bone augmentation. Regen Biomater. 2021 Mar 13;8(2):rbaa060. doi: 10.1093/rb/rbaa060. PMID: 33738113; PMCID: PMC7955717.


  1. Miura KI, Katase N, Sumi M, Umeda M, Yamada T. A Case Report of Primary Intraosseous Carcinoma of the Mandible Initially Diagnosed as Mandibular Osteomyelitis. Cureus. 2025 Feb 12;17(2):e78892. doi: 10.7759/cureus.78892. PMID: 40091999; PMCID: PMC11909620.


  1. Aoki Y, Ishikawa K, Miura K, Sugimoto K, Nakayama T, Fujimoto Y, Kobayashi Y. Protective effect of angiotensin II receptor blocker and calcium channel blocker on endothelial vasomotor function after everolimus-eluting stent implantation. J Cardiol. 2016 Mar;67(3):236-40. doi: 10.1016/j.jjcc.2015.05.006. Epub 2015 Jul 17. PMID: 26194867.


  1. Koga T, Minamizato T, Kawai Y, Miura K, I T, Nakatani Y, Sumita Y, Asahina I. Bone Regeneration Using Dentin Matrix Depends on the Degree of Demineralization and Particle Size. PLoS One. 2016 Jan 21;11(1):e0147235. doi: 10.1371/journal.pone.0147235. PMID: 26795024; PMCID: PMC4721666.


  1. Miura K, Yoshida M, Yamaguchi K, Yoshida R, Asahina I. Sonographic Evaluation of Bone Formation After Sagittal Split Ramus Osteotomy. J Ultrasound Med. 2016 Feb;35(2):395-400. doi: 10.7863/ultra.15.04046. Epub 2016 Jan 18. PMID: 26782159.


  1. Ohba S, Nakao N, Kawasaki T, Miura KI, Minamizato T, Koga Y, Yoshida N, Asahina I. Skeletal stability after sagittal split ramus osteotomy with physiological positioning in patients with skeletal mandibular prognathism and facial asymmetry. Br J Oral Maxillofac Surg. 2016 Oct;54(8):920-926. doi: 10.1016/j.bjoms.2016.06.010. Epub 2016 Jun 29. PMID: 27372232.


  1. Miura K, Yoshida M, Asahina I. Secondary bone grafting with simultaneous auto-tooth transplantation to the alveolar cleft. J Oral Maxillofac Surg. 2015 Jun;73(6):1050-7. doi: 10.1016/j.joms.2015.01.004. Epub 2015 Jan 20. PMID: 25857282.


  1. Matsui A, Matsui K, Handa T, Tanuma Y, Miura K, Kato Y, Kawai T, Suzuki O, Kamakura S, Echigo S. The regenerated bone quality by implantation of octacalcium phosphate collagen composites in a canine alveolar cleft model. Cleft Palate Craniofac J. 2014 Jul;51(4):420-30. doi: 10.1597/12-096. Epub 2013 Jan 31. PMID: 23369014.


  1. Ohba S, Tominaga J, Koga T, Miura KI, Yoshida N, Asahina I. Movement of the proximal segment after intraoral vertical ramus osteotomy versus short lingualosteotomy with physiological positioning strategy. J Craniomaxillofac Surg. 2020 Jul;48(7):638-644. doi: 10.1016/j.jcms.2020.04.006. Epub 2020 Apr 25. PMID: 32439368.


  1. Sanuki T, Mishima G, Kurata S, Watanabe T, Kiriishi K, Tachi M, Ozaki Y, Okayasu I, Kawai M, Matsushita Y, Miura K, Ayuse T. Comparison of the hemodynamic effects of propofol and ketamine as anesthetic induction agents during high-dose remifentanil administration: a single-center retrospective comparative study. J Dent Anesth Pain Med. 2015 Sep;15(3):129-134. doi: 10.17245/jdapm.2015.15.3.129. Epub 2015 Sep 30. PMID: 28879269; PMCID: PMC5564168.


  1. Sanuki T, Miura K, Watanabe T, Ayuse T. Transcutaneous vocal cord ultrasonography after oral and maxillofacial surgery requiring intermaxillary fixation: A technical report. Eur J Anaesthesiol. 2016 Aug;33(8):598-9. doi: 10.1097/EJA.0000000000000443. PMID: 26945153.


  1. Miura K, Nakaya H, Kobayashi Y. Experimental assessment of effects of antiproliferative drugs of drug-eluting stents on endothelial cells. Cardiovasc Revasc Med. 2015 Sep;16(6):344-7. doi: 10.1016/j.carrev.2015.07.002. Epub 2015 Jul 9. PMID: 26253188.


  1. Hara M, Nomura K, Sumi M, Katase N, Miura KI, Yamada T. Carbon ion radiotherapy and AI chemotherapy for soft tissue sarcoma of the temporomandibular joint: A case report of 5-year disease-free survival without wide resection. J Stomatol Oral Maxillofac Surg. 2026 Mar;127(2):102616. doi: 10.1016/j.jormas.2025.102616. Epub 2025 Oct 9. PMID: 41067416.


  1. Tanaga K, Miura K, Kageyama T, Nakamura Y, Inoue T, Jo K, Ishikawa T, Miyazaki A. Restenosis after implantation of sirolimus-eluting stent begins suddenly, shows short term progression, and stops suddenly. J Cardiol. 2011 Jul;58(1):26-31. doi: 10.1016/j.jjcc.2011.03.004. Epub 2011 May 26. PMID: 21616642.


  1. Otsuru M, Hasegawa T, Yamakawa N, Okura M, Yamada SI, Hirai E, Inomata T, Saito H, Miura KI, Furukawa K, Naruse T, Yanamoto S, Umeda M. A Multicenter Study on the Effect of Margin Distance on Survival and Local Control in Stage 1-2 Squamous Cell Carcinoma of the Tongue. Ann Surg Oncol. 2023 Feb;30(2):1158-1166. doi: 10.1245/s10434-022-12462-8. Epub 2022 Sep 20. PMID: 36125567.